FREQUENTLY ASKED QUESTIONS

The gel is preferably used in the evening, before going to bed.
See leaflet for use: Remain in the lying position for about 1 minute. Please make sure that your pelvis remains elevated. This ensures the necessary distribution of the vaginal gel on the cervix.

In rare cases, burning or itching may occur when using DeflaGyn®. The acidic pH values of DeflaGyn® (pH = 3) could trigger these sensations, especially if the vagina is dry or if the vaginal mucosa is very thin and cracked. Stop using DeflaGyn® for a few days to see if there is any improvement. If the symptoms persist, contact your doctor to clarify the cause.

DeflaGyn® vaginal gel should only be used during pregnancy after consulting a doctor!
Since no studies have been carried out on DeflaGyn® with pregnant women, your doctor will decide whether you can use the gel.

In the Instructions for Use of DeflaGyn® vaginal gel you will find the following note: What should be considered before use? „Shake the bottle well before use! The inserted gel can partially flow out after use. Any gel that has leaked out can look slightly reddish and discolor your underwear. This discoloration can be washed out. You can also use a laundry protector.“ This reddish color is caused by the antioxidant selenium compound contained in the gel. If the reddish colored gel now flows off, this is sometimes mistakenly referred to as „bleeding“ by the users.

If you use the “pill” for contraception, you can use DeflaGyn® vaginal gel at the same time without any problems. Then take the therapy break provided when using DeflaGyn® during the pill break during the withdrawal bleeding. If you use a pill that is taken continuously, keep the 3-day therapy break with DeflaGyn® as described in the package insert after 28 days.

The simultaneous use of DeflaGyn® vaginal gel and products that remain in the vagina (e.g. vaginal rings) can limit the effectiveness of these products and is therefore contraindicated.
Additional local treatments in the vagina, such as the use of suppositories, vaginal tablets, other vaginal gels, etc. should therefore take place at least 2 hours before or after the use of DeflaGyn®. Preferably, you can also have one treatment in the morning and one in the evening.

Usually, it is recommended to use DeflaGyn® vaginal gel in the evening before going to bed. But you can also choose a different time. It is important that you carry out the application according to the instructions for use, remain in a lying position for about 1 minute and make sure that your pelvis remains elevated.

Sexual intercourse is allowed at any time while using DeflaGyn® vaginal gel! Both without and with a condom.

DeflaGyn® vaginal gel does not affect the safety of condoms. DeflaGyn® does not contain any ingredients that affect the material of condoms. This also applies to very thin condoms.
To prevent HPV infections in the genital and anal area, you should always use a condom, especially if you change sex partners frequently. Safer sex does not offer reliable protection against HPV because the HP virus can be transmitted by smear infection. However, condoms can reduce the risk of infection.

Unfortunately, the influence of DeflaGyn® vaginal gel on sperm quality has not been checked in previous studies.
In principle, sperm are sensitive to changes in pH. An alkaline environment stimulates sperm motility, an acidic pH value inhibits the sperm’s motility. The ideal pH value for the ascent of the sperm and their survival time is pH 7.0 – 7.8. This corresponds to the pH value of the seminal fluid. At a pH value below 6.5, the sperm motility decreases sharply. DeflaGyn® vaginal gel has an acidic pH value of 3 due to the citric acid it contains. If you wish to have children, it is therefore recommended that you pause the use of DeflaGyn® vaginal gel on the fertile days around ovulation and only continue it afterwards.

A preventive use of DeflaGyn® vaginal gel has not yet been tested. The scientific data on DeflaGyn® relate to the application to Promote Spontaneous Remission and Regression of Unclear Cervical Smears (ASCUS, ASC-H, LSIL, HSIL / PAP II-p, PAP III-p, PAP IIID1, PAP IIID2 (Munich III) / PAP III, PAP IIID) or HPV-Induced- or p16/Ki-67 Positive Cervical Lesions or Cervical Erosions. Based on the current scientific data, we cannot recommend the preventive use of DeflaGyn®.

The currently available study results relate exclusively to the application to Promote Spontaneous Remission and Regression of Unclear Cervical Smears (ASCUS, ASC-H, LSIL, HSIL / PAP II-p, PAP III-p, PAP IIID1, PAP IIID2 (Munich III) / PAP III, PAP IIID) or HPV-Induced- or p16/Ki-67 Positive Cervical Lesions or Cervical Erosions. Unfortunately, there is no experience of using it with other test results.
Your doctor will discuss the necessary further procedure or treatment method with you in detail.

DeflaGyn® vaginal gel should not be stored above 25 ° C. At room temperatures above 25 ° C, it is recommended to store DeflaGyn® in the refrigerator.

The use of DeflaGyn® vaginal gel does not affect the preventive effect of a hormone or copper IUD.

Unfortunately, there is currently no experience or study data on the use of DeflaGyn® vaginal gel with simultaneous endometriosis. In any case, you should consult with your doctor to determine whether an application would be possible.

All available study results relate to an application period of 3x 28 days.
Non-menstruating patients
DeflaGyn® should be used for a duration of 3 x 28 days. After 28 days of treatment, please stop using DeflaGyn® intravaginal gel for 3 days. Then continue treatment for another 28 days and stop for another 3 days. Afterwards continue with the third treatment cycle.
Menstruating patients
Do not use DeflaGyn® intravaginal gel while you are menstruating (approx. 3-5 days/cycle). It is not necessary to stop treatment for another 3 days, as menstruation already counts as a treatment break. You can start using DeflaGyn® intravaginal gel on any day of your cycle.

Unfortunately, no study data or experience reports are available on the treatment of genital warts with DeflaGyn® vaginal gel.

The simultaneous use of DeflaGyn® vaginal gel and products which remain in the vagina (e.g. vaginal rings) could reduce the effectiveness of these products and is therefore contraindicated.

DeflaGyn® vaginal gel can be used after healing, after about 1-2 weeks.

After a local surgery like a conization patient should wait until wound healing process is finished. Estimated time for wound healing is about 4 to 6 weeks in case of a conization. Afterwards it´s possible to start with application of DeflaGyn® vaginal gel. Please follow your doctor´s advice.

Normal vaginal secretions contain not only mucous membrane cells but also approx. 100 million germs per ml, primarily lactic acid bacteria. Presumably, when the vaginal gel drains, a small amount of lactic acid bacteria is also adsorbed and transported away.
The effect of DeflaGyn® Vaginal gel on physiologic vaginal flora has not been investigated in studies so far.
The pH value of DeflaGyn® vaginal gel is approx. 3 due to the citric acid it contains. This acidic pH value supports and stabilizes the natural vaginal environment.

Yes, DeflaGyn® vaginal gel can be used immediately after local antibiotic therapy.

An influence of DeflaGyn® vaginal gel on the cycle could not be observed so far and can be completely excluded due to the way the gel works.

The inserted gel may partially flow out after use. This gel that may have leaked can look slightly reddish and discolor your underwear. This discoloration can be washed out. You can also use protective clothing. „This reddish color is caused by the antioxidant selenium compound contained in the gel. If the reddish-colored gel now flows off, it is sometimes mistakenly referred to by users as“ bleeding „.

Vaginal atrophy is especially a problem in menopause due to hormonal changes. However vaginal atrophy can occur at any age, although one main cause is a decrease in estrogenic stimulation of the urogenital tissues. DeflaGyn® Vaginal Gel is not intended to treat vaginal atrophy.

DeflaGyn® Vaginal gel is not covered by health insurance.

The dispensing of DeflaGyn® Vaginal Gel only after a doctor’s prescription is subject to national legislation. DeflaGyn® can be obtained without a prescription in most countries. However, the use should always be preceded by a doctor’s advice and recommendation.